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Antibodies against endogenous retroviruses promote lung cancer immunotherapy.

Nature · 2023 · PMC10115647 · PMID 37046094

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B cell depletion increased relapse rates and subsequently decreased survival of G12Ci-treated KPAR G12C -challenged mice, similarly to CD8 + T cell depletion; however, this effect did not reach statistical significance (Fig. 3e ), indicating that G12Ci may contribute to immunological memory against tumour relapse.

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