Barely Significant
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Network pharmacology mechanism of Scutellarin to inhibit RGC pyroptosis in diabetic retinopathy.

Sci Rep · 2023 · PMC10119430 · PMID 37081038

Europe PMCDOI
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a decreasing trendP < 0.05actually significant
Compared with the DR group, the average optical density of GSDMD in the SCU treatment group showed a decreasing trend (P < 0.05) (Fig. 2 B).

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showed a trendno p-value reported
In our study, the mean optical density of caspase-1 in the diabetic group was significantly increased compared with the normal group, and it showed a trend of decrease in RGC in the SCU group, compared with the diabetic group 20 , which suggests that SCU can reduce the inflammatory response of DR, especially in RGC.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.