Single-cell transcriptomic landscape identifies the expansion of peripheral blood monocytes as an indicator of HIV-1-TB co-infection.

Although the differences did not reach statistical significance among the three groups due to the limited sample size, these data will serve as a reference to investigate the role of T/NK cell subsets in HIV-1-TB co-infection in future studies. 2.4 Seven subclusters of naïve T cells identified using PBMC scRNA-seq Early activation of naïve T cells involves better control of Mtb growth ( Urdahl et al., 2011 ), while lymphoid tissue injury caused due to HIV-1 infection depletes the number of naïve T cells ( Zeng et al., 2012 ).

also in 111,027 other papers