Myeloid Src-family kinases are critical for neutrophil-mediated autoinflammation in gout and motheaten models.

J Exp Med · 2023 · PMC10120404 · PMID 37074415

Europe PMC DOI

hedged sentences

0.2600

closest p · 5.2× alpha

0.2600

boldest claim

The sentences

did not reach statistical significanceP = 0.26not close (p > 0.1)

This difference between the two limbs tended to be less prominent in Hck −/− Fgr −/− Lyn −/− mice, although the overall difference between the two genotypes did not reach statistical significance (P = 0.26).

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highly significantno p-value reported

Together with associated pathologies such as obesity, hypertension, cardiovascular diseases, and chronic kidney disease, gout causes highly significant morbidity and mortality ( Danve and Neogi, 2020 ; Dalbeth et al., 2019 ).

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