The human P2X7 receptor alters microglial morphology and cytokine secretion following immunomodulation.

Front Pharmacol · 2023 · PMC10123291 · PMID 37101546

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a slight trendno p-value reported

Still, a slight trend was observed: in both genotypes treated with either one of the two P2X7R antagonists, the levels of TNFα, INF-γ, and partially IL-6—all highly proinflammatory cytokines–were found to have a mean coefficient of ≤ 1.

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did not reach statistical significanceno p-value reported

Overall, changes in microglia numbers did not reach statistical significance ( Figure 3A ).

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