Comparative Efficacy of Novel Antidiabetic Drugs on Albuminuria Outcomes in Type 2 Diabetes: A Systematic Review.

The magnitudes of mean UACR change from baseline with saxagliptin were greater in the eGFR < 30 and 30–50 ml/min/1.73 m 2 subgroups at − 245.2 mg/g and − 105.0 mg/g, respectively, although in the former subgroup it did not reach statistical significance; a smaller but significant improvement in UACR (− 19.3 mg/g; P = 0.033) was observed in the eGFR > 50 ml/min/1.73 m 2 subgroup [ 58 ].

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