An unbiased AAV-STARR-seq screen revealing the enhancer activity map of genomic regions in the mouse brain in vivo.

We observed a general positive correlation between the STARR-seq signal strengths (RNA/DNA log2 fold change of the mapped reads signal) and the relative fluorescence levels of the VS, but this correlation was relatively weak and did not reach statistical significance likely due to the limited number of tested sequences (Pearson’s correlation coefficient = 0.61, p = 0.08) (Fig. 3 B).

also in 111,027 other papers