Multiple PIK3CA mutation clonality correlates with outcomes in taselisib + fulvestrant-treated ER+/HER2-, PIK3CA-mutated breast cancers.

Genome Med · 2023 · PMC10131374 · PMID 37101291

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did not reach statistical significanceno p-value reported

In the SANDPIPER ctDNA dataset, we observed a trend of fewer alterations in PI3K (excluding PIK3CA ) pathway genes in samples with clonal vs subclonal multiple PIK3CA mut, however this did not reach statistical significance.

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