Obstructive sleep apnoea and 5-year cognitive decline in the elderly.

In Model 1, lower mean S pO 2 (as a continuous variable) was associated with incidence of significant decline in FCSRT delayed free recall (OR for 1% decrease 1.21, p=0.007; corresponding to a decline of ≥3.2 points during follow-up); a trend towards significance was observed in the other models (OR 1.22, p=0.010, according to Model 2 and OR 1.22, p=0.011, according to Model 3).

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Participants with hypoxic burden ≥42%min·h −1 showed a trend towards higher likelihood of significant decline in phonemic fluency (OR 2.26, p=0.033, according to Model 3) ( supplementary tables S10 and S11 ).

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