It is worth noting that the relative abundances of Alishewanella , Cloacibacterium , and Vagococcus all showed an increasing trend on day 5 (the first day of the drug withdrawal period) in group L compared with group CK, which may be related to the doxycycline concentration in group L.
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Doxycycline Attenuates Pig Intestinal Microbial Interactions and Changes Microbial Metabolic Pathways.
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On day 33, the drug metabolism by other enzyme pathways in group H was significantly upregulated ( p < 0.05), which in group L also showed a trend of upregulation.