Successive Waves of the COVID-19 Pandemic Had an Increasing Impact on Chronic Cardiovascular Patients in a Western Region of Romania.

Ischemic heart disease worsened the odds of patients’ survival irrespective of the three pandemic waves (Breslow–Day test, p = 0.387), with a marginally significant Mantel–Haenszel common estimate for risk: OR = 1.604, 95% (0.996; 2.586).

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Older age and male gender were confirmed as highly significant predictors of unfavorable outcomes.

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When we separately considered each group, the association did not reach statistical significance for any of them, but the aggregate OR (the common estimate for risk) was similar, although marginally significant.

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