Integrated analysis of methylation profiles and transcriptome of Marek's disease virus-infected chicken spleens reveal hypomethylation of CD4 and HMGB1 genes might promote Marek's disease tumorigenesis.

Poult Sci · 2023 · PMC10140160 · PMID 37043960

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showed a trendno p-value reported

DNA methylation in promoter showed a trend of decline with a bottom point at TSS, and then the methylation level increases continuously from TSS to TES.

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a decreasing trendno p-value reported

We observed a decreasing trend of CpG methylation levels in the promoter, which reached a minimum at the TSS, and then increased continuously from the TSS to the TTS.

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