Notably, although it did not reach statistical significance, pioglitazone plus exercise reduced the liver lipid content (measured by liver proton magnetic resonance spectroscopy) more than pioglitazone alone (−2.6 ± 1.4% vs. −1.5 ± 1.3, p = 0.6), hinting at a potential beneficial role of exercise training in NAFLD in PWH [ 185 ].
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