17 , 18 Although our recent results are in line with these findings, we have also found that, in contrast to men, women exhibit a negative trend regarding GDF15 correlation with obesity. 19 In keeping with this, injection of recombinant GDF15 in mice and monkeys reduced their weight 20 and overexpression of Gdf15 in mice has been reported to result in obesity resistance and improved insulin sensitivity 21 whereas Gdf15 deletion
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