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Wiskott-Aldrich syndrome protein interacts and inhibits diacylglycerol kinase alpha promoting IL-2 induction.

Front Immunol · 2023 · PMC10149931 · PMID 37138877

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However, in co-silencing experiments, the reduction of IL-2 upon NCK-1 silencing failed to reach statistical significance; this may be due to the residual NCK-1 protein that may still play its function ( Supplementary Materials 6C, D, F ).

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