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Sustained Shugoshin 1 downregulation reduces tumor growth and metastasis in a mouse xenograft tumor model of triple-negative breast cancer.

Cell Div · 2023 · PMC10150544 · PMID 37122033

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Results Tumor growth and metastasis to the lymph nodes and lungs were significantly reduced in the shRNA SGO1 -treated mice group, while metastasis to the liver tends to be lower in cells with downregulated SGO1, but it did not reach statistical significance.

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