Barely Significant
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The effect of metformin on influenza vaccine responses in nondiabetic older adults: a pilot trial.

Immun Ageing · 2023 · PMC10152024 · PMID 37131271

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a strong trendno p-value reported
Thus, metformin treatment showed a strong trend to improve cTfh vaccination responses, however no significant differences were observed in antibody responses with treatment.

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