Barely Significant
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The burden of rare protein-truncating genetic variants on human lifespan.

Nat Aging · 2022 · PMC10154195 · PMID 37117740

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nominally significantP < 0.05actually significant
After exclusion of BRCA2 , BRCA1 , TET2 and ATM , 38 pathways remained nominally significant ( P < 0.05), suggesting that further genes therein will reach gene-level significant association with lifespan when sample sizes for PTV-burden analyses increase further.

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