showed a trendp=0.054
Patients with mMRC grade 1 showed a trend towards a higher risk of exacerbation in GOLD A groups (p=0.054) and a significantly increased risk of exacerbation in GOLD B (p<0.0001) compared with patients with mMRC grade 0. 58 In GOLD A/B groups with a high prevalence of mMRC grade 1, patients had significantly lower pulmonary function (p<0.0