In this context, gene set enrichment analysis using the microarray gene expression data from IL-33-expressing HEK293 cells showed a trend toward altered expression levels of GATA3 target genes under hypoxia ( SI Appendix , Fig.
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Hypoxia induces downregulation of the tumor-suppressive sST2 in colorectal cancer cells via the HIF-nuclear IL-33-GATA3 pathway.
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