Adolescent anxiety and pain problems: A joint, genome-wide investigation and pathway-based analysis.

Combined QNTS and QLSCD sample As 4,028,157 polymorphisms were shared and the phenotypic distribution did not differ between the two cohorts (Mann-Whitney U test = 132,241.000, SE = 4,945.508, p = 0.925 and Mann-Whitney U test = 128,134.500, SE = 4,946.462, p = 0.356 for pain problems and anxiety symptoms, respectively), we merged the genomic regions for which we found nominally significant results in both the QNTS and QLSCD to achieve stronger statistical power and thus test the robustness of the previous findings.

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