Left Ventricular Systolic Function After 3 Months of SGLT2 Inhibitor Therapy in Heart Failure Patients with Reduced Ejection Fraction.

While the improvement in the indices of GCW and GWW was numerically more in the SGLT2i+ group than in the SGLT2i− group, these results did not reach statistical significance ( p = 0.084 and p =0.894 respectively) (Fig. 1 c, d, respectively; Table 2 ). 3D Left Ventricular Ejection Fraction and LV Global Longitudinal Strain The entire cohort achieved statistically significant improvement from baseline to follow-up in 3D LVEF and LV GLS parameters ( p < 0.001 and p < 0.001, respectively) (Fig. 2 ).

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