Impaired alveolar macrophage 11β-hydroxysteroid dehydrogenase type 1 reductase activity contributes to increased pulmonary inflammation and mortality in sepsis-related ARDS.

Front Immunol · 2023 · PMC10172463 · PMID 37180160

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0.1220

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0.1220

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did not reach statistical significancep=0.122not close (p > 0.1)

In sepsis patients with ARDS, a trend towards lower AM HSD-1 reductase activity was observed in patients who died within 30 days of ICU admission compared to those who survived, however this did not reach statistical significance (data not shown, medians 0.052 v 0.185 pM/hr/10 6 AMs, p=0.122).

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