Heparanase-2 protein and peptides have a protective effect on experimental glomerulonephritis and diabetic nephropathy.

Front Pharmacol · 2023 · PMC10172501 · PMID 37180718

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Similarly, DN type 2 mice treated with the HPSE1 inhibitor SST0001 showed a trend of increased HPSE2 expression ( Figure 3C ).

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