Association of baseline ROR1 and ROR2 gene expression with clinical outcomes in the I-SPY2 neoadjuvant breast cancer trial.

Breast Cancer Res Treat · 2023 · PMC10175386 · PMID 37029329

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a negative trendno p-value reported

An exploratory analysis of pCR in HR- HER2- patients by treatment arm indicated a negative trend for the association of high-level ROR1 with pCR in 5 of the 8 treatment arms with a notably strong signal in the 32 patients treated with MK2206, an AKT inhibitor.

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