Analysis of DCF fluorescence, which detects many types of ROS, showed a trend towards an increase in Gem- and His-only treated cells and a significant increase ( p < 0.05) in cells treated with a combination of both drugs compared to control ( Figure 3 B).
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Histidine Enhances the Anticancer Effect of Gemcitabine against Pancreatic Cancer via Disruption of Amino Acid Homeostasis and Oxidant-Antioxidant Balance.
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