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Immunomodulatory Effects of the Pea Defensin Psd1 in the Caco-2/Immune Cells Co-Culture upon <i>Candida albicans</i> Infection.

Int J Mol Sci · 2023 · PMC10178127 · PMID 37175419

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Moreover, the increase in several cytokines, such as IL-12 ( p = 0.0087), IL-15 ( p = 0.013), IL-27 ( p = 0.011), and chemokine MCP-1 ( p = 0.024) in response to incubation with Psd1 was statistically significant in moDCs, but failed to reach statistical significance in case of monocytes ( Supporting Materials, Table S1 ).

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