Predictors of Response to Fremanezumab in Migraine Patients with at Least Three Previous Preventive Failures: Post Hoc Analysis of a Prospective, Multicenter, Real-World Greek Registry.

J Clin Med · 2023 · PMC10179256 · PMID 37176658

Europe PMC DOI

hedged sentences

0.0710

closest p · 1.4× alpha

0.0710

boldest claim

The sentences

a marked trendp = 0.071so close (0.05 < p ≤ 0.1)

Notably, the presence of allodynia showed a marked trend to significance towards association with a clinically meaningful response to fremanezumab (OR: 1.5; 95% CI: 0.6–3.3; p = 0.071).

also in 109 other papers

failed to reach significanceno p-value reported

Super-responders more frequently presented allodynia both in univariate (OR of 2.4; 95% CI: 1.2–4.8; p = 0.022) and multivariate logistic regression (OR of 2.1; 95% CI: 1.4–6.8; p = 0.04) analyses, compared to responders, while all other associations failed to reach significance ( Table 3 ). 4.

also in 714 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.