It has been shown that the rostral substantia nigra regions of PD patients showed a trend towards decreased MI and total creatine (creatine + phosphocreatine, tCr) ratio compared with healthy controls whereas in the caudal substantia nigra regions the MI/Cr ratios were increased in PD patients compared with healthy controls [ 87 , 88 ].
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Cyclitols: From Basic Understanding to Their Association with Neurodegeneration.
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