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<i>CTLA4</i> mRNA is downregulated by miR-155 in regulatory T cells, and reduced blood <i>CTLA4</i> levels are associated with poor prognosis in metastatic melanoma patients.

Front Immunol · 2023 · PMC10183574 · PMID 37197667

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Although the results from the US cohort did not reach statistical significance, similar trends were observed in patients.

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