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Anesthetic management of the traumatic brain injury patients undergoing non-neurosurgery.

Anesth Pain Med (Seoul) · 2023 · PMC10183618 · PMID 37183278

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showed a trendno p-value reported
Currently, there is not sufficient data to reach a definitive conclusion—although hypertonic saline showed a trend towards lower mortality and a more beneficial effect on CPP compared to mannitol, there were no statistically significant differences in mortality and neurological outcomes between hypertonic saline and mannitol administration [ 14 ].

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