Novel Fas-TNFR chimeras that prevent Fas ligand-mediated kill and signal synergistically to enhance CAR T cell efficacy.

Mol Ther Nucleic Acids · 2023 · PMC10185706 · PMID 37200859

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did not reach statistical significanceno p-value reported

24 , 25 , 26 , 27 We also observed a trend for Fas-CD40 upregulating CCL3 , CCL4 , and CCL5 transcription; however, this did not reach statistical significance.

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