Association of CYP2R1 and CYP27B1 genes with the risk of obesity and vitamin D metabolism in Saudi women.

J Genet Eng Biotechnol · 2023 · PMC10185724 · PMID 37184736

Europe PMC DOI

hedged sentence

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closest p · 1.2× alpha

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boldest claim

The sentences

close to borderline significancep < 0.06so close (0.05 < p ≤ 0.1)

Results Our result shows that hypermethylation in site 2 of the CYP2R1 gene with body weight ( p < 0.004), BMI ( p < 0.002), waist circumference ( p < 0.002), total-LDL ( p < 0.027), total cholesterol ( p < 0.022), and vitamin D (VD) (close to borderline significance p < 0.06) and site 4 of CYP2R1 with LDL ( p < 0.041) in the four tested sites among normal and obese women was significantly associated.

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