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Cellular and molecular insights into incomplete immune recovery in HIV/AIDS patients.

Front Immunol · 2023 · PMC10185893 · PMID 37205108

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found that although the difference in sTNF-RI and sTNF-RII levels between INRs and IRs did not reach statistical significance, the levels of sTNF-RII in INRs were higher than those found in healthy subjects and were more comparable to those observed in viremic subjects ( 191 ). 5 Conclusions and perspectives In summary, CD4 + T cell homeostasis alteration in HIV-infected subjects with incomplete immune reconstitution despite successful viral suppression during ART, including decreased quantity and altered quality.

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