Trophozoite fitness dictates the intestinal epithelial cell response to Giardia intestinalis infection.

PLoS Pathog · 2023 · PMC10187934 · PMID 37141303

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a negative trendno p-value reported

This revealed that addition of “fit” trophozoites indeed counteracted the IEC response to lysed trophozoites, as evident from significantly lowered levels of five out of seven transcripts tested, namely CXCL3 , CXCL8 , IL1A , IL1B , and TNF , and a negative trend also for CXCL1 ( Fig 3B ; IEC attachment data presented in S5B Fig ).

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