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Design and rationale of the CHILL phase II trial of hypothermia and neuromuscular blockade for acute respiratory distress syndrome.

Contemp Clin Trials Commun · 2023 · PMC10191700 · PMID 37228902

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showed a trendno p-value reported
Exclusion of patients with high vasopressor requirements is based on the CASS trial [ 26 ], which showed a trend toward increased mortality due to refractory shock in the TH arm.

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