The impact of heart failure therapy in patients with mildly reduced ejection fraction: a network meta-analysis.

ESC Heart Fail · 2023 · PMC10192281 · PMID 36896801

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Regarding higher values of LVEF, the comparison was not statistically significant but showed a trend for better results with sacubitril/valsartan up to 62.5% of LVEF. 23 Even so, only with EMPEROR‐Preserved 33 we begin to look at HF with LVEF ≥40% differently.

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