Characterization of antigen-specific CD8+ memory T cell subsets in peripheral blood of patients with multiple sclerosis.

Front Immunol · 2023 · PMC10192904 · PMID 37215118

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a decreasing trendno p-value reported

In our experiments, despite an irregular change in total MOG-specific CD8 + T cells in MS patients, MOG-specific CD8 + T CM and CD8 + T EM exhibited a decreasing trend at 14 and 28 d post-treatment with teriflunomide, a well-known immunosuppressant agent ( 30 ).

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did not reach statistical significanceno p-value reported

OND patients demonstrated slightly higher expression of Tim-3 on MOG-specific CD8 + T EM and CD8 + T CM than HC, but did not reach statistical significance ( Figures 3E, J ).

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