Antiviral effects of the fused tricyclic derivatives of indoline and imidazolidinone on ZIKV infection and RdRp activities of ZIKV and DENV.

1 A and 1 B ) show that compared to the ZIKV control, twelve compounds of 11 – 17, 19, 20 , and 26 – 28 are potent agents against ZIKV infection with quite significant differences (*** P < 0.001) while six compounds of 1, 3, 5, 10, 21 and 23 express much weak anti-ZIKV activities with significant differences (** P < 0.01).

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