Transparent neural interfaces: challenges and solutions of microengineered multimodal implants designed to measure intact neuronal populations using high-resolution electrophysiology and microscopy simultaneously.

Subdurally implanted ECoG arrays showed no differences in reactive astrocyte accumulation 2 months following device implantation; however, there was a strong trend toward an increase in GFAP staining on the ipsilateral side, suggesting the presence of mild reactive gliosis in the implanted cortex in the case of the SWCNT/MDPE/Pt ECoG array 124 .

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