The shed P2X7 receptor is an index of adverse clinical outcome in COVID-19 patients.

Front Immunol · 2023 · PMC10196164 · PMID 37215142

Europe PMC DOI

hedged sentences

0.0570

closest p · 1.1× alpha

0.0570

boldest claim

The sentences

near significancep = 0.057so close (0.05 < p ≤ 0.1)

Shed P2X7R positively correlated with ALT (r = 0.269; p = 0.012) and negatively with BNP (r = -0.361; p = 0.007), indexes of liver and heart injury or stress, respectively, and, at near significance, with sNLRP3 (r = 0.218; p = 0.057) ( Table 6 ).

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did not reach statistical significanceno p-value reported

Soluble P2X7R was significantly elevated in patients of all these subgroups, except in patients admitted to ICU, where sP2X7R increase did not reach statistical significance, and in patients who died after hospital discharge.

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