Deletion of p75^NTR rescues the synaptic but not the inflammatory status in the brain of a mouse model for Alzheimer's disease.

With this approach, no significant difference could be observed between the experimental groups (Two-way RM ANOVA: F (3, 76) = 2.407, p = 0.074); however, APP/PS1tg mice showed a trend toward a decrease in the input/output curve which was not present in APP/PS1tg x p75 NTR KO and control mice ( Figure 1A ).

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