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The ubiquitination status of the glucagon receptor determines signal bias.

J Biol Chem · 2023 · PMC10200972 · PMID 37037304

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Recruitment of βarr2 with FYVE endosomes was also better with GCGR-K333R than GCGR-WT but failed to reach statistical significance as compared with the association induced by GCGR-WT ( Fig. 6 G ).

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