Dietary palmitoleic acid reprograms gut microbiota and improves biological therapy against colitis.

Also, compared with TNBS-treated mice receiving water, TNBS-treated mice receiving palmitoleic acid (POA) showed a significant trend of increased colon length (Supplementary Figure 13D) and displayed less ulceration, milder colonic tissue damage, much fewer infiltrations of inflammatory cells in intestinal barrier and less goblet cell loss (Supplementary Figure 13, E to G), particularly higher expression of epithelial markers including ZO-1 and Occludin (Supplementary Figure 13 H), and lower frequency of CD8 + , ly6G + and CD11b + cells in colonic lamina propria (Supplementary Figure 13, I and J).

also in 9,775 other papers