Intensive compared with less intensive blood pressure control to prevent adverse cardiac remodelling in children with chronic kidney disease (HOT-KID): a parallel-group, open-label, multicentre, randomised, controlled trial.

Lancet Child Adolesc Health · 2023 · PMC10202819 · PMID 36442482

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did not reach statistical significanceno p-value reported

There was a sustained reduction in LVMI over the course of the trial, but the difference between groups did not reach statistical significance ( figure 2A ; table 2 ).

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