Emerging Therapies for the Management of Pain and Vaso-Occlusive Crises in Patients With Sickle Cell Disease: A Systematic Review of Randomized Controlled Trials.

Cureus · 2023 · PMC10204617 · PMID 37223201

Europe PMC DOI

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an interesting trendno p-value reported

did not demonstrate a benefit with vitamin D in the study assessed in this review [ 8 ], this same research group had previously identified an interesting trend.

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did not reach statistical significanceno p-value reported

Another two of the treatment therapies (SC411, NAC) were found to be effective but did not reach statistical significance.

also in 17,681 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.