Hypoxia extends lifespan and neurological function in a mouse model of aging.

Again, we observed large increases in the expression of these senescence markers in kidney and liver of Ercc1 Δ/- mice relative to wild type; however, levels of Cdkn2a were unaffected by hypoxia ( S1B Fig ), and although levels of Cdkn1a trended slightly lower in hypoxia ( S1C Fig ), the difference did not reach statistical significance.

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