A randomized controlled trial of effects of open-label placebo compared to double-blind placebo and treatment-as-usual on symptoms of allergic rhinitis.

When comparing OLP with DBP we found that OLP was superior to DBP with respect to TNSS (12 h, Z = − 2.68, p = 0.007, Bonferroni corrected p = 0.021, r = 0.41; TNSS 2 weeks, p > 0.10) and showed a trend for significance for CSMS (12 h, Z = − 1.67, p = 0.095, corrected p > 0.10, r = 0.26; 2 weeks, Z = − 1.80, p = 0.073, corrected p > 0.10, r = 0.28) (RQLQ, p > 0.10).

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