The amount of Cer-EOS product formed by PNPLA1 trun from dilinolein was 3.62-fold greater than that formed from diolein, while no such difference was apparent in the incubations with ATGL trun ( Fig. 7 A, D).
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Recombinant PNPLA1 catalyzes the synthesis of acylceramides and acyl acids with selective incorporation of linoleic acid.
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