Adolescent exposure to the Spice/K2 cannabinoid JWH-018 impairs sensorimotor gating and alters cortical perineuronal nets in a sex-dependent manner.

Transl Psychiatry · 2023 · PMC10209055 · PMID 37225721

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closest p · 1.2× alpha

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The sentences

a strong trendp = 0.06so close (0.05 < p ≤ 0.1)

Accordingly, the perimeter of microglia soma showed a strong trend to increase in the short term (p = 0.06) (Fig. 5B, G ) while this enhancement was significant in the long-term (p < 0.05) (Fig. 5E, G ) in these animals.

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almost significantp = 0.06so close (0.05 < p ≤ 0.1)

We also found an almost significant decrease in the percentage of PV neurons surrounded by PNNs in the IL of male, but not in female (Supplementary Fig. 3 ), mice in both the short- (p = 0.06) and long-term (p = 0.059) (Fig. 4A, D, G ).

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